PI Publications
- 2024LCN2 promotes focal adhesion formation and invasion by stimulating Src activation. bioRxiv.
Choudhary BS, Chaudhary N, Vijan A, Mandal D, Pilankar L, Gawand S, Khan B, Shivashankar A, Doloi R, Joshi N, Das M, Dalal SN (2024).
14-3-3σ restricts YY1 to the cytoplasm, promoting therapy resistance, and tumor progression in colorectal cancer. International Journal of Cancer.Lonare A, Raychaudhuri K, Shah S, Madhu G, Sachdeva A, Basu S, Thorat R, Gupta S, Dalal SN (2024)
14-3-3ε conditional knockout mice exhibit defects in the development of the epidermis. FEBS Letters.Tilwani S, Gandhi K, Dalal SN (2024)
- 2023Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration. FEBS Letters.
Choudhary B, Chaudhary N, Shah M, Dwivedi N, Smitha PK, Das M, Dalal SN
ΔNp63 overexpression promotes oral cancer cell migration through hyperactivated Activin A signaling. Experimental Cell Research.431(1):113739. PMID: 37567436Mundhe D, Mishra R, Basu S, Dalal S, Kumar S, Teni T (2023).
Elevated translationally controlled tumour protein promotes oral cancer progression and poor outcome. Journal of Oral Pathology and Medicine. PMID: 37573872.Sharma D, Pawar SN, Sulkshane P, Waghole R, Yasser M, Pawar SS, Kannan S, Chaudhary N, Kalwar A, Patil R, Nair S, Dalal SN, Teni T (2023).
- 2022Plakophilin3 loss leads to increased adenoma formation and rectal prolapse in APCmin mice, Biochemical and Biophysical Research Communications, Volume 586, 1 January 2022, Pages 14-19
Rahul Raghavan, Navami Koyande, Rohit Beher, Neha Chetlangia, Mukta Ramadwar, Shital Pawade, Rahul Thorat, Jolanda van Hengel, Tetyana Sklyarova, Frans van Roy, Sorab N. Dalal
Atypical activation of signaling downstream of inactivated Bcr-Abl mediates chemoresistance in chronic myeloid leukemia. Journal of Cell Communication and Signaling. 16(2):207-222. 2022. PMID: 34596797.Narasimhan M, Khamkar V, Tilwani S, Dalal SN, Shetty D, Subramanian PG, Gupta S, Govekar R
Plakophilin3 loss leads to an increase in autophagy and radio-resistance. Biochemical and Biophysical Research Communications.Chaudhary N, Joshi N, Doloi R, Shivashankar A, Thorat R, Dalal S
- 2021Lipocalin 2 expression promotes tumor progression and therapy resistance by inhibiting ferroptosis in colorectal cancer, Int J Cancer, doi: 10.1002/ijc.33711 PMID: 34146401
Chaudhary N, Choudhary BS, Shah SG, Khapare N, Dwivedi N, Gaikwad A, Joshi N, Raichanna J, Basu S, Gurjar M, Smitha PK, Saklani A, Gera P, Ramadwar M, Patil P, Thorat R, Gota V, Dhar SK, Gupta S, Das M, Dalal SN
14-3-3γ prevents centrosome duplication by inhibiting NPM1 function. Genes Cells, 26(6):426-446. PMID: 33813791Bose A, Modi K, Dey S, Dalvi S, Nadkarni P, Sudarshan M, Kundu TK, Venkatraman P, Dalal SN
Tumor-specific overexpression of histone gene, H3C14 in gastric cancer is mediated through EGFR-FOXC1 axis.Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms.13:194703. PMID: 33727172.Rashid M, Shah SG, Verma T, Chaudhary N, Sukanya, Patel VB, Gera PB, Smoot D, Ashaktorab H, Dalal SN, Gupta S
Atypical activation of signaling downstream of inactivated Bcr-Abl mediates chemoresistance in chronic myeloid leukemia. Journal of Cell Communication and Signaling.Narasimhan M, Khamkar V, Tilwani S, Dalal SN, Shetty D, Subramanian PG, Gupta S, Govekar R
Disruption of desmosome function leads to increased centrosome clustering in 14-3-3γ-knockout cells with supernumerary centrosomes, Volume595, Issue21, November 2021, Pages 2675-2690Sarika Tilwani, Karan Gandhi, Satya Narayan, Rama Koti Ainavarapu, Sorab Nariman Dalal
- 2019
- 2018Plakoglobin localization to the cell border restores desmosome function in cells lacking 14-3-3γ. Biochem Biophys Res Commun. 495(2): 1998-2003. PMID: 29253567
Vishal SS, Tilwani S, Dalal SN
Plakophilin3 loss leads to an increase in lipocalin2 expression, which is required for tumour formation. Exp Cell Res. 369(2): 251-265. PMID: 29803740Basu S, Chaudhary N, Shah S, Braggs C, Sawant A, Vaz S, Thorat R, Gupta S, Dalal SN
Plakophilin3 increases desmosome assembly, size and stability by increasing expression of desmocollin2, Biochemical and Biophysical Research Communications, Volume 495, Issue 1, 1 January 2018, Pages 768-774Mansa Gurjar, Kumar Krishna Raychaudhuri, Snehal Mahadika, Divya Reddy, Apurva Atak, Trupti Shetty Kruthi Rao, Mansi S. Karkhanis, Prajakta Gosavi, Lalit Sehgal, Sanjay Gupta, Sorab N. Dalal
- 2017Generation of mice with tissue specific transgene expression using sperm mediated gene transfer. Int J Pharm Biosci.8(2): 324-329.
Vishal SS, Tilwani S, Thorat R, Dalal SN
- 201614-3-3sigma loss leads to activation of the epithelial to mesenchymal transition due to the stabilization of c-Jun. J Biol Chem 291: 16068 - 16081
Raychaudhuri K, Chaudhary N, Gurjar M, D'Souza R, Limzerwala J, Maddika S, Dalal SN.
14-3-3γ prevents centrosome amplification and neoplastic progression.Mukhopadhyay A, Sehgal L, Bose A, Gulvady A, Senapati P, Thorat R, Basu S, Bhatt K, Hosing AS, Balyan R, Borde L, Kundu TK, Dalal SN.
- 2015MMP7 is required to mediate cell invasion and tumor formation upon plakophilin3 loss.
Basu S, Thorat R, Dalal SN.
Loss of the desmosomal plaque protein plakophilin3 does not induce the epithelial mesenchymal transition. J Biosci Tech 6: 647-652Gurjar M, Raychaudhari K, Dalal SN.
Plakophilin3 and Plakoglobin recycling are differentially regulated during the disassembly of desmosomes. J Biosci Tech 6: 634-642.Raychaudhari K, Gurjar M, Dalal SN.
- 2014Generation of transgenic mice by exploiting spermatogonial stem cells in vivo. Methods Mol Biol 1194: 327-337.
Sehgal L, Usmani, A. Dalal SN, Majumdar, SS.
14-3-3gamma mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo. J Cell Sci 127: 2174-2188Sehgal L, Mukhopadhyay A, Rajan A, Khapare N, Sawant M, Vishal SS, Bhatt K, Ambatipudi S, Antao N, Alam H, Gurjar M, Basu S, Mathur R, Borde L, Hosing AS, Vaidya MM, Thorat R, Samaniego F, Kolthur-Seetharam U, Dalal SN.
- 2013Understanding the role of keratins 8 and 18 in neoplastic potential of breast cancer derived cell lines. PLoS One 8:e53532.
Iyer SV, Dange PP, Alam H, Sawant SS, Ingle AD, Borges AM, Shirsat NV, Dalal SN, Vaidya MM.
- 2012Generation of HIV-1 based bi-cistronic lentiviral vectors for stable gene expression and live cell imaging. Indian J Exp Biol 50:669-676.
Sehgal L, Budnar S, Bhatt K, Sansare S, Mukhopadhaya A, Kalraiya RD, Dalal SN.
Fascin overexpression promotes neoplastic progression in Oral Squamous Cell Carcinoma. BMC Cancer 12:32.Alam H, Bhate AV, Gangadaran P, Sawant SS, Salot S, Sehgal L, Dange PP, Chaukar DA, D'Cruz A K, Kannan S, Gude R, Kane S, Dalal SN, Vaidya MM.
Plakophilin3 Loss Leads to an Increase in PRL3 Levels Promoting K8 Dephosphorylation, Which Is Required for Transformation and Metastasis. PLoS One 7:e38561.Khapare N, Kundu ST, Sehgal L, Sawant M, Priya R, Gosavi P, Gupta N, Alam H, Karkhanis M, Naik N, Vaidya MM, Dalal SN
- 2011E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly. Cell Mol Life Sci 68:1439-1454.
Gosavi P, Kundu ST, Khapare N, Sehgal L, Karkhanis MS, Dalal SN.
Lentiviral mediated transgenesis by in vivo manipulation of spermatogonial stem cells. PLoS One 6:e21975.Sehgal L, Thorat R, Khapare N, Mukhopadhaya A, Sawant M, Dalal SN.
Filamin A stimulates cdc25C function and promotes entry into mitosis. Cell Cycle 10:776-782.Telles E, Gurjar M, Ganti K, Gupta D, Dalal SN.
Loss of keratins 8 and 18 leads to alterations in alpha6beta4-integrin-mediated signalling and decreased neoplastic progression in an oral-tumour-derived cell line. J Cell Sci 124:2096-2106.Alam H, Kundu ST, Dalal SN, Vaidya MM.
Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells. Mol Biol Cell 22:4068-4078.Alam H, Sehgal L, Kundu ST, Dalal SN, Vaidya MM.
- 2009A novel pocket in 14-3-3epsilon is required to mediate specific complex formation with cdc25C and to inhibit cell cycle progression upon activation of checkpoint pathways. Exp Cell Res 315:1448-1457.
Telles E, Hosing AS, Kundu ST, Venkatraman P, Dalal SN.
- 200814-3-3 Gamma is required to enforce both the incomplete S phase and G2 DNA damage checkpoints. Cell Cycle 7:3171-3179.
Hosing AS, Kundu ST, Dalal SN
Plakophilin3 down regulation leads to a decrease in cell adhesion and promotes metastasis. Int J Cancer 123:2303-2314.Kundu ST, Gosavi P, Khapare N, Patel R, Hosing AS, Maru GB, Ingle A, Decaprio JA, Dalal SN.
- 2005
- 200414-3-3 family members act coordinately to regulate mitotic progression. Cell Cycle 3:672-677.
Dalal SN, Yaffe MB, DeCaprio JA.
- 200014-3-3 transits to the nucleus and participates in dynamic nucleo-cytoplasmic transport. J. Cell Biol. 156:817-828.
Brunet A, Kanai F, Stehn J, Xu J, Sarbassova D, Frangioni JV, Dalal SN, DeCaprio JA, Greenberg ME, Yaffe MB.
- 1999Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site. Mol. Cell. Biol. 19:4465-4479.
Dalal SN, Schweitzer CM, Gan J, DeCaprio JA.