PI Publications
- 2024cFLIP – An interacting partner and a novel substrate for pro-apoptotic serine protease HtrA2 . Biochemistry and Biophysics Reports. 38: 101682.
Natu K, Dutta S, Bose K (2024).
Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions. Cell Chemical Biology.König C, Ivanisenko N, Hillert-Richter L, Namjoshi D, Natu K, Espe J, Reinhold D, Kolchanov N, Ivanisenko V, Kähne T, Bose K, Lavrik I (2024)
- 2023Purification of hetero-oligomeric protein variants using a modified tandem affinity purification approach. STAR Protocols. 4(1): 102036.
Parui AL, Bose K.
Expanding the clinical phenotype of FADD deficiency with a novel mutation and its role in Fas-mediated apoptotic pathway. British Journal of Haematology.Setia P, Bargir UA, Shanmukhaiah C, Jodhawat N, Gaikwad P, Vedpathak D, Dutta S, Kulkarni R, Kambli P, Dalvi A, Shinde S, Gupta M, Nambiar N, Sawant S, Shelar S, Dhawale A, Mohanty M, Yadav RM, Bose K, Madkaikar M.
- 2022Regulation of extrinsic apoptotic signaling by c-FLIP: towards targeting cancer networks. Trends in Cancer. 8(3):190-209.
Ivanisenko N, Seyrek K, Hiller-Richter L, König C, Espe J, Bose K, Lavrik I
Unraveling the dichotomy of enigmatic serine protease HtrA2. Frontiers in Molecular Biosciences.Chakraborty A, Bose R, Bose K
Role of conserved regulatory loop residues in allosteric propagation of serine protease HtrA2. Biochemical and Biophysical Research CommunicationsParui A, Singh N, Dutta S, Bose K
Textbook on Cloning, Expression and Purification of Recombinant Proteins. Singapore; Springer, 2022. (ISBN 978-981-16-4986-8)Bose K (Editor)
"Purification of Difficult Proteins." In: Bose K. (Ed.) Textbook on Cloning, Expression and Purification of Recombinant Proteins. Singapore; Springer, 2022. Pp. 249-278. (ISBN: 978-981-16-4986-8)Acharya S, Bose R, Bose K
"Protein Purification by Ion Exchange Chromatography." In: Bose K. (Ed.) Textbook on Cloning, Expression and Purification of Recombinant Proteins. Singapore; Springer, 2022. Pp.173-198. (ISBN: 978-981-16-4986-8)Chakraborty A, Puja R, Bose K
"Transformation and Protein Expression." In: Bose K. (Ed.) Textbook on Cloning, Expression and Purification of Recombinant Proteins. Springer, Singapore; Springer, 2022. Pp. 83-114. (ISBN: 978-981-16-4986-8)Deshmukh S, Kulkarni R, Bose K
"Selection of Cloning and Expression Plasmid Vectors." In: Bose K. (Ed.) Textbook on Cloning, Expression and Purification of Recombinant Proteins. Singapore; Springer, 2022. Pp. 57-81. (ISBN: 978-981-16-4986-8)Kulkarni R, Bose R, Bose K
"Protein Quantitation and Detection." In: Bose K. (Ed.) Textbook on Cloning, Expression and Purification of Recombinant Proteins. Singapore; Springer, 2022.Kummari R, Puja R, Bose K
Purification, characterization and functional site prediction of the vaccinia-related kinase 2A small transmembrane domain. MethodsX. 9:101704. PMID: 35518920Puja R, Chakraborty A, Dutta S, Bose K
Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2. Structure. PMID: 35738282Parui A, Mishra V, Dutta S, Bhaumik P, Bose K
- 2021Loss of GSK-3â mediated phosphorylation in HtrA2 contributes to uncontrolled cell death with Parkinsonian phenotype. International Journal of Biological Macromolecules. 180:97-111. PMID: 33716130
Bose K, Wagh A, Mishra V, Dutta S, Parui A, Puja R, Pandav-Mudrale S, Kulkarni S, Gai P, Sarin R (2021)
Elucidating the role of GRIM-19 as a substrate and allosteric activator of pro-apoptotic serine protease HtrA2. Biochemical Journal. PMID: 33650635Kummari R, Dutta S, Patil S, Pandav-Mudrale S, Bose K (2021)
- 2020A distinct concerted mechanism of structural dynamism defines activity of human serine protease HtrA3. Biochemical Journal. 477(2):407-429. PMID: 31899476
Acharya S, Dutta S, Bose K (2020)
Dual specificity phosphatase 9: A novel binding partner cum substrate of proapoptotic serine protease HtrA2. Biochemical and Biophysical Research Communications. 533: 607-612. PMID: 32988583Acharya S, Dutta S, Pandav-Mudrale S, Bose K (2020)
- 2019Identification of a distal allosteric ligand binding pocket in HtrA3. Biochemical and Biophysical Research Communications (2019) . 516(4): 1130-1136. PMID: 31280864
Acharya S, Dutta S, Chopra S, Bose K
Structural modeling and role of HAX-1 as a positive allosteric modulator of human serine protease HtrA2 (2019). Biochemical Journal. 476(20): 2965-2980. PMID: 31548268Chaganti LK, Dutta S, Kuppili RR, Mandal M, Bose K
Discerning the mechanism of action of HtrA4: a serine protease implicated in the cell death pathway (2019). Biochemical Journal. 476(10): 1445-1463. PMID: 3103671564. Kummari R, Dutta S, Chaganti LK, Bose K
14-3-3 proteins mediate the localization of Centrin2 to centrosome (2019). Journal of Biosciences. 44: 42. PMID: 31180055Bose A, Dalal SN
- 2018PDZscape: a comprehensive PDZ-protein database. BMC Bioinformatics
Doshi J, Kuppili R, Gurdasani S, Venkatakrishnan N, Saxena A, Bose K.
- 2017Histone isoform H2A1H promotes attainment of distinct physiological states by altering chromatin dynamics. Epigenetics Chromatin.
Bhattacharya S, Reddy D, Jani V, Gadewal N, Shah S, Reddy R, Bose K, Sonavane U, Joshi R, Gupta S.
- 2016Insights into the mechanism of human papillomavirus E2-induced procaspase-8 activation and cell death. Sci. Rep.
Singh N, Senapati, S and Bose K.
Incorporation of a tag helps to overcome expression variability in a recombinant host. iotechnol Rep (Amst).Bhattacharya S, Reddy D, Reddy R, Sharda A, Bose K, Gupta S.
- 2015Molecular basis of death effector domain chain assembly and its role in caspase-8 activation.
Singh N, Hassan A, Bose K.
- 2014Dual regulatory switch confers tighter control on HtrA2 proteolytic activity.
Singh N, D’Souza A, Cholleti A, Sastry GM and Bose K.
Dual regulatory switch confers tighter control on HtrA2 proteolytic activity.Singh N, D’Souza A, Cholleti A, Sastry GM and Bose K.
- 2013Intricate structural coordination and domain plasticity regulate activity of serine protease HtrA2.
Chaganti LK, Kuppili RR, Bose K.
Allosteric regulation of serine protease HtrA2 through novel non-canonical substrate binding pocket.Bejugam PR, Kuppili RR, Singh N, Gadewal N, Chaganti LK, Sastry GM, Bose K.
- 2011he structural basis of mode of activation and functional diversity: a case study with HtrA family of serine proteases
Singh N, Kuppili RR, Bose K.
Design and characterization of an enhanced repressor of human papillomavirus E2 protein.Bose K, Meinke G, Bohm A and Baleja JD
- 2009Disorder and Structure in the Rab11 Binding Domain of Rab11 Family Interacting Protein 2.
Wei J, Liu Y, Bose K, Henry GD and Baleja JD.
- 2007The Role of Conserved Histidines in the Structure and Stability of Human Papillomavirus Type 16 E2 DNA Binding Domain. Biochemistry.
Bose K, Yoder NC, Kumar K and Baleja JD.
- 2005pH Effects on the Stability and Dimerization of Procaspase-3.
Bose K and Clark AC.
- 2003An Uncleavable Procaspase-3 Mutant has a Lower Catalytic Efficiency but an Active Site Similar to That of Mature Caspase-3.
Bose K, Pop C, Feeney B, and Clark AC.
- 2001Dimeric Procaspase-3 Unfolds via a Four-State Equilibrium Process.
Bose K and Clark AC.
Removal of the Pro-domain Does Not Affect the Conformation of the Procaspase-3 Dimer.Pop C, Chen Y-R, Smith B, Bose K, Bobay B, Tripathy A, Franzen S and Clark AC