PI Publications
- 2022Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins. Proceedings of the National Academy of Sciences. 26;119(17):e2119644119. doi: 10.1073/pnas.2119644119. PMID: 35439056.
Mukherjee S, Maddalena M, Lü Y, Martinez S, Nataraj NB, Noronha A, Sinha S, Teng K, Cohen-Kaplan V, Ziv T, Arandkar S, Hassin O, Chatterjee R, Pirona AC, Shreberk-Shaked M, Gershoni A, Aylon Y, Elazar Z, Yarden Y, Schramek D, Oren M.
- 2021TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment. Proceedings of the National Academy of Sciences. 118(23):e2025631118. PMID: 34088837
Maddalena M, Mallel G, Nataraj NB, Shreberk-Shaked M, Hassin O, Mukherjee S, Arandkar S, Rotkopf R, Kapsack A, Lambiase G, Pellegrino B, Ben-Isaac E, Golani O, Addadi Y, Hajaj E, Eilam R, Straussman R, Yarden Y, Lotem M, Oren M
- 2020Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53‐associated features. Molecular Oncology
Gal Benor, Garold Fuks, Suet-Feung Chin, Oscar M. Rueda, Saptaparna Mukherjee, Sharathchandra Arandkar, Yael Aylon, Carlos Caldas, Eytan Domany and Moshe Oren
- 2018Altered p53 functionality in cancer-associated fibroblasts contributes to their cancer-supporting features. PNAS
Sharathchandra Arandkar, Noa Furth, Yair Elisha*, Nishanth belugali Nataraj*, Heiko van der Kuip, Yosef Yarden, Walter Aulitzky, Igor Ulitsky, Benjamin Geiger and Moshe Oren. (* authors contributed equally)
Po-303 Modified p53 functionality in cancer-associated fibroblasts promotes cancer growth. ESMO Open Cancer HorizonsSharathchandra Arundkar, N Furth, Y Elisha, N Nataraj, HVD Kuip, W Aulitzky, I Ulitsky, B Geiger and M Oren.
- 2016Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery. Scientific Reports
Kristin Stock, Marta F. Estrada, Suzana Vidic,; Kjersti Gjerde; Albin Rudisch; Vítor Espírito Santo; Michaël Barbier, Sami Blom, Sharath C Arundkar, et al, Ralph Graeser
- 2015p53-dependent non-coding RNA networks in chronic lymphocytic leukemia. Leukemia
Blume CJ, Hotz-Wagenblatt A, Hüllein J, Sellner L, Jethwa A, Stolz T, Slabicki M, Lee K, Sharathchandra A, et al, Zenz T
Reversible induction of translational isoforms of p53 in glucose deprivation. Cell Death and DifferentiationKhan D, Katoch A, Das A, Sharathchandra A, Lal R, Roy P, et al
- 2014IRES mediated translational regulation of p53 isoforms. Wiley Interdiscip Rev RNA
Sharathchandra A, Katoch A, Das S
- 2012Annexin A2 and PSF proteins interact with p53 IRES and regulate translation of p53 mRNA. RNA biology
Sharathchandra A, Lal R, Khan D, Das S
Effect of a natural mutation in the 5′ untranslated region on the translational control of p53 mRNA. OncogeneKhan D, Sharathchandra A, Ponnuswamy A, Grover R, Das S
- 2011Effect of mutations on the p53 IRES RNA structure: implications for de-regulation of the synthesis of p53 isoforms. RNA biology
Grover R*, Sharathchandra A*, Ponnuswamy A, Khan D, Das S. (* authors contributed equally)