PI Publications

2024
Antibodies target intracellular oncodrivers through PIGR-mediated transcytosis. Genes & Immunity. 25(1):85-86.PMID: 38092884.
Biswas S, Anadon CM, Conejo-Garcia JR (2024)
Key players of immunosuppression in epithelial malignancies: Tumor-infiltrating myeloid cells and γδ T cells
Tamuli B, Sharma S, Patkar M, Biswas S (2024)
AXL/GAS6 signaling governs differentiation of tumor-associated macrophages in breast cancer. Experimental Cell Research.
Purohit S, Mandal G, Biswas S, Dalui S, Gupta A, Roy Chowdhury S, Bhattacharyya A (2024)
2023
Actionable spontaneous antibody responses antagonize malignant progression in ovarian carcinoma. Gynecologic Oncology. 173: 114-121.
Handley KF, Mehta S, Martin AL, Biswas S, Maharaj K, Nagy MZ, Mine JA, Cortina C, Yu X, Sprenger K, Mandal G, Innamarato P, Powers JJ, Harro CM, Chaurio RA, Anadon CM, Shahzad MM, Flores I, Conejo-Garcia JR.
Sézary syndrome originates from heavily mutated hematopoietic progenitors. Blood Advances. 2023 Sep 26;7(18):5586-5602. doi: 10.1182/bloodadvances.2022008562. PMID: 37531660
Harro CM, Sprenger KB, Chaurio RA, Powers JJ, Innamarato P, Anadon CM, Zhang Y, Biswas S, Mandal G, Mine JA, Cortina C, Nagy MZ, Martin AL, Handley KF, Borjas GJ, Chen PL, Pinilla-Ibarz J, Sokol L, Yu X, Conejo-Garcia JR
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers. Immunity.
Biswas S, Mandal G, Anadon C, Chaurio R, Lopez-Bailon L, Nagy M, Mine J, Hänggi K, Sprenger K, Innamarato P, Harro C, Powers J, Johnson J, Fang B, Eysha M, Nan X, Li R, Perez B, Curiel T, Yu X, Rodriguez P, Conejo-Garcia J
2022
Neglected no more: B cell-mediated anti-tumor immunity. Semin Immunol. 2023 Jan;65:101707. doi: 10.1016/j.smim.2022.101707. Epub 2022 Dec 15. Review. PubMed PMID: 36527759.
Conejo-Garcia JR, Biswas S, Chaurio R, Rodriguez PC
Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells. Cancer Cell. 2022 May 9;40(5):545-557.e13. doi: 10.1016/j.ccell.2022.03.008. Epub 2022 Apr 14. PubMed PMID: 35427494; PubMed Central PMCID: PMC9096229.
Anadon CM, Yu X, Hänggi K, Biswas S, Chaurio RA, Martin A, Payne KK, Mandal G, Innamarato P, Harro CM, Mine JA, Sprenger KB, Cortina C, Powers JJ, Costich TL, Perez BA, Gatenbee CD, Prabhakaran S, Marchion D, Heemskerk MHM, Curiel TJ, Anderson AR, Wenham RM, Rodriguez PC, Conejo-Garcia JR
Olfactory Receptor OR2H1 is an effective target for CAR T cells in human epithelial tumors. Mol Cancer Ther. 2022 May 2;. doi: 10.1158/1535-7163.MCT-21-0872. [Epub ahead of print] PubMed PMID: 35499393.
Martin AL, Anadon CM, Biswas S, Mine JA, Handley KF, Payne KK, Mandal G, Chaurio RA, Powers JJ, Sprenger KB, Rigolizzo KE, Innamarato P, Harro CM, Mehta S, Perez BA, Wenham RM, Conejo- Garcia JR
IgA-Dominated Humoral Immune Responses Govern Patients' Outcome in Endometrial Cancer. Cancer Res. 2022 Mar 1;82(5):859- 871. doi: 10.1158/0008-5472.CAN-21-2376. PubMed PMID: 34949671; PubMed Central PMCID: PMC8898267.
Mandal G, Biswas S, Anadon CM, Yu X, Gatenbee CD, Prabhakaran S, Payne KK, Chaurio RA, Martin A, Innamarato P, Moran C, Powers JJ, Harro CM, Mine JA, Sprenger KB, Rigolizzo KE, Wang X, Curiel TJ, Rodriguez PC, Anderson AR, Saglam O, Conejo-Garcia JR
TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. Immunity. 2022 Jan 11;55(1):115-128.e9. doi: 10.1016/j.immuni.2021.12.007. PubMed PMID: 35021053; PubMed Central PMCID: PMC8852221.
Chaurio RA, Anadon CM, Lee Costich T, Payne KK, Biswas S, Harro CM, Moran C, Ortiz AC, Cortina C, Rigolizzo KE, Sprenger KB, Mine JA, Innamarato P, Mandal G, Powers JJ, Martin A, Wang Z, Mehta S, Perez BA, Li R, Robinson J, Kroeger JL, Curiel TJ, Yu X, Rodriguez PC, Conejo-Garcia JR
2021
IgA transcytosis and antigen recognition govern ovarian cancer immunity. Nature. 2021 Mar;591(7850):464-470. doi: 10.1038/s41586-020-03144-0. Epub 2021 Feb 3. PubMed PMID: 33536615; PubMed Central PMCID: PMC7969354.
Biswas S, Mandal G, Payne KK, Anadon CM, Gatenbee CD, Chaurio RA, Costich TL, Moran C, Harro CM, Rigolizzo KE, Mine JA, Trillo-Tinoco J, Sasamoto N, Terry KL, Marchion D, Buras A, Wenham RM, Yu X, Townsend MK, Tworoger SS, Rodriguez PC, Anderson AR, Conejo-Garcia JR
Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice. J Clin Invest. 2021 Feb 1;131(3). doi: 10.1172/JCI135711. PubMed PMID: 33270606; PubMed Central PMCID: PMC7843215.
Harro CM, Perez-Sanz J, Costich TL, Payne KK, Anadon CM, Chaurio RA, Biswas S, Mandal G, Rigolizzo KE, Sprenger KB, Mine JA, Showe LC, Yu X, Liu K, Rodriguez PC, Pinilla-Ibarz J, Sokol L, Conejo-Garcia JR
2020
Humoral immune responses: Unsung heroes of the war on cancer. Semin Immunol. 2020 Jun;49:101419. doi: 10.1016/j.smim.2020.101419. Epub 2020 Nov 9. Review. PubMed PMID: 33183950; PubMed Central PMCID: PMC7738315.
Conejo-Garcia JR, Biswas S, Chaurio R
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells. Science. 2020 Aug 21;369(6506):942-949. doi: 10.1126/science.aay2767. PubMed PMID: 32820120; PubMed Central PMCID: PMC7646930.
Payne KK, Mine JA, Biswas S, Chaurio RA, Perales-Puchalt A, Anadon CM, Costich TL, Harro CM, Walrath J, Ming Q, Tcyganov E, Buras AL, Rigolizzo KE, Mandal G, Lajoie J, Ophir M, Tchou J, Marchion D, Luca VC, Bobrowicz P, McLaughlin B, Eskiocak U, Schmidt M, Cubillos-Ruiz JR, Rodriguez PC, Gabrilovich DI, Conejo-Garcia JR
Comparison of histopathological grading and staging of breast cancer with p53-positive and transforming growth factor-beta receptor 2-negative immunohistochemical marker expression cases. Cancer translational medicine. 2020 August; 6(2):30-33. doi: 10.4103/ctm.ctm_4_20.
Mandal PK, Adhikari A, Biswas S, Giri A, Gupta A, Bhattacharyya A
The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling. Immunity. 2020 Apr 14;52(4):668-682.e7. doi: 10.1016/j.immuni.2020.03.004. PubMed PMID: 32294407; PubMed Central PMCID: PMC7207019.
Mohamed E, Sierra RA, Trillo-Tinoco J, Cao Y, Innamarato P, Payne KK, de Mingo Pulido A, Mandula J, Zhang S, Thevenot P, Biswas S, Abdalla SK, Costich TL, Hänggi K, Anadon CM, Flores ER, Haura EB, Mehrotra S, Pilon-Thomas S, Ruffell B, Munn DH, Cubillos-Ruiz JR, Conejo-Garcia JR, Rodriguez PC
2019
Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer. J Immunol. 2019 Dec 15;203(12):3447-3460. doi: 10.4049/jimmunol.1900692. Epub 2019 Nov 8. PubMed PMID: 31704881; PubMed Central PMCID: PMC6994919. *Equal contribution.
Biswas S*, Mandal G*, Roy Chowdhury S, Purohit S, Payne KK, Anadon C, Gupta A, Swanson P, Yu X, Conejo-Garcia JR, Bhattacharyya A
A Nuclear Zip Code in SKS1 mRNA Promotes Its Slow Export, Nuclear Retention, and Degradation by the Nuclear Exosome/DRN in Saccharomyces cerevisiae. J Mol Biol. 2019 Sep 6;431(19):3626-3646. doi: 10.1016/j.jmb.2019.07.005. Epub 2019 Jul 8. PubMed PMID: 31295459.
Das S, Biswas S, Chaudhuri S, Bhattacharyya A, Das B
RelA driven co- expression of CXCL13 and CXCR5 is governed by a multifaceted transcriptional program regulating breast cancer progression. Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1;1865(2):502-511. doi: 10.1016/j.bbadis.2018.12.002. Epub 2018 Dec 12. PubMed PMID: 30553016.
Biswas S, Roy Chowdhury S, Mandal G, Purohit S, Gupta A, Bhattacharyya A
2018
Heterodimer formation by Oct4 and Smad3 differentially regulates epithelial-to-mesenchymal transition-associated factors in breast cancer progression. Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt A):2053-2066. doi: 10.1016/j.bbadis.2018.03.010. Epub 2018 Mar 8. PubMed PMID: 29526821.
Mandal G, Biswas S, Roy Chowdhury S, Chatterjee A, Purohit S, Khamaru P, Chakraborty S, Mandal PK, Gupta A, de la Mare JA, Edkins AL, Bhattacharyya A
Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapy. J Leukoc Biol. 2018 May;103(5):799-805. doi: 10.1002/JLB.5HI1117-446RR. Epub 2018 Mar 14. PubMed PMID: 29537705; PubMed Central PMCID: PMC6004318.
Perales-Puchalt A, Perez-Sanz J, Payne KK, Svoronos N, Allegrezza MJ, Chaurio RA, Anadon C, Calmette J, Biswas S, Mine JA, Costich TL, Nickels L, Wickramasinghe J, Rutkowski MR, Conejo- Garcia JR
CCL2 conditionally determines CCL22-dependent Th2-accumulation during TGF- β-induced breast cancer progression. Immunobiology. 2018 Feb;223(2):151-161. doi: 10.1016/j.imbio.2017.10.031. Epub 2017 Oct 16. PubMed PMID: 29107385. *Equal contribution.
Mandal PK*, Biswas S*, Mandal G, Purohit S, Gupta A, Majumdar Giri A, Roy Chowdhury S, Bhattacharyya A
2017
miR-216b suppresses breast cancer growth and metastasis by targeting SDCBP. Biochem Biophys Res Commun. 2017 Jan 1;482(1):126-133. doi: 10.1016/j.bbrc.2016.10.003. Epub 2016 Oct 5. PubMed PMID: 27720715.
Jana S, Sengupta S, Biswas S, Chatterjee A, Roy H, Bhattacharyya A
2016
Aggregation induced emission enhancement of pyrene-appended Schiff base luminophore and its photovoltaic effect. Journal of luminescence. 2016 February; 175:44-49. doi: https://doi.org/10.1016/j.jlumin.2016.02.007.
Panda U, Roy S, Mallick D, Dalapati P, Biswas S, Manik NB, Bhattacharyya A, Sinha C
2015
Low fucose containing bacterial polysaccharide facilitate mitochondria-dependent ROS-induced apoptosis of human lung epithelial carcinoma via controlled regulation of MAPKs-mediated Nrf2/Keap1 homeostasis signaling. Mol Carcinog. 2015 Dec;54(12):1636-55. doi: 10.1002/mc.22236. Epub 2014 Oct 30. PubMed PMID: 25358602. *Equal contribution.
Chowdhury SR, Sengupta S*, Biswas S*, Sen R, Sinha TK, Basak RK, Adhikari B, Bhattacharyya A
p53-dependent expression of CXCR5 chemokine receptor in MCF-7 breast cancer cells. Sci Rep. 2015 Mar 19;5:9330. doi: 10.1038/srep09330. PubMed PMID: 25786345; PubMed Central PMCID: PMC4365401.
Mitkin NA, Hook CD, Schwartz AM, Biswas S, Kochetkov DV, Muratova AM, Afanasyeva MA, Kravchenko JE, Bhattacharyya A, Kuprash DV
2014
Bacterial fucose-rich polysaccharide stabilizes MAPK-mediated Nrf2/Keap1 signaling by directly scavenging reactive oxygen species during hydrogen peroxide-induced apoptosis of human lung fibroblast cells. PLoS One. 2014;9(11):e113663. doi: 10.1371/journal.pone.0113663. eCollection 2014. PubMed PMID: 25412177; PubMed Central PMCID: PMC4239092. *Equal contribution.
Roy Chowdhury S, Sengupta S*, Biswas S*, Sinha TK, Sen R, Basak RK, Adhikari B, Bhattacharyya A
CXCL13-CXCR5 co-expression regulates epithelial to mesenchymal transition of breast cancer cells during lymph node metastasis. Breast Cancer Res Treat. 2014 Jan;143(2):265-76. doi: 10.1007/s10549-013-2811-8. Epub 2013 Dec 13. PubMed PMID: 24337540.
Biswas S, Sengupta S, Roy Chowdhury S, Jana S, Mandal G, Mandal PK, Saha N, Malhotra V, Gupta A, Kuprash DV, Bhattacharyya A
2013
Cooperative involvement of NFAT and SnoN mediates transforming growth factor-β (TGF-β) induced EMT in metastatic breast cancer (MDA-MB 231) cells. Clin Exp Metastasis. 2013 Dec;30(8):1019-31. doi: 10.1007/s10585-013- 9600-y. Epub 2013 Jul 6. PubMed PMID: 23832742.
Sengupta S, Jana S, Biswas S, Mandal PK, Bhattacharyya A

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