PI Publications
- 2024Histone acetylation: A key determinant of acquired cisplatin resistance in cancer. Clinical Epigenetics. 16:8.
Natu A, Verma T, Khade B, Thorat R, Gera P, Dhara S, Gupta S (2024)
Integrative epigenome-transcriptome analysis unravels cancer-specific over-expressed genes potentially regulating immune microenvironment in clear cell renal cell carcinoma.Biochimica et Biophysica Acta (BBA) - General SubjectsGadewal N, Natu A, Sen S, Rauniyar S, Bastikar V, Gupta S (2024)
Global DNA methylation level in spermatozoa is not associated with ICSI fertilization outcome and embryo quality in donor oocyte programme. Human Fertility 27(1): 2421191.Pandya RK, Salian SR, Lakshmi VR, Uppangala S, Kalthur G, Gupta S, Adiga SK (2024).
- 2023Mitochondrial dysfunction and chromatin changes with autophagy-mediated survival in doxorubicin resistant cancer cell lines. Biochemical and Biophysical Research Communications.
Natu A, Pedgaonkar A, Gupta S
Raman spectroscopy revealed cell passage-dependent distinct biochemical alterations in radiation-resistant breast cancer cells. ACS Omega.Rauniyar S, Pansare K, Sharda A, Singh S, Saha P, CM Krishna, Gupta S
An increase in polyadenylation of histone isoforms, Hist1h2ah and Hist2h3c2, is governed by 3'-UTR in de-differentiated and undifferentiated hepatocyte. Experimental Biology & Medicine.Verma T, Natu A, Khade B, Gera P, Gupta S
Human solid tumors and clinical relevance of the enhanced permeation and retention effect: a 'golden gate' for nanomedicine in preclinical studies? Nanomedicine.Gawali P, Saraswat A, Bhide S, Gupta S, Patel K
Differential sperm histone retention in normozoospermic ejaculates of infertile men negatively affects sperm functional competence and embryo quality. Andrology. PMID: 37801310Pandya RK, Jijo A, Cheredath A, Uppangala S, Salian SR, Lakshmi VR, Kumar P, Kalthur G, Gupta S, Adiga SK (2023).
Epithelial-to-mesenchymal transition status correlated with ultrastructural features, and TP53 mutation in patient-derived oral cancer cell lines. Molecular Biology Reports. 50(10):8469-8481. PMID: 37639153Navarange SS, Bane SM, Mehta D, Shah S, Gupta S, Waghmare SK (2023)
- 2022DNA methylation mediated downregulation of histone H3 variant H3.3 affects cell proliferation contributing to the development of HCC.Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.1868: 166284.PMID: 34626773
Reddy D, Bhattacharya S, Shah S, Rashid M, Gupta S
Atypical activation of signaling downstream of inactivated Bcr-Abl mediates chemoresistance in chronic myeloid leukemia. Journal of Cell Communication and Signaling. 16(2):207-222. 2022. PMID: 34596797.Narasimhan M, Khamkar V, Tilwani S, Dalal SN, Shetty D, Subramanian PG, Gupta S, Govekar R
Combinatorial Cetuximab targeted polymeric nanocomplexes reduce PRC1 level and abrogate growth of metastatic hepatocellular carcinoma in vivo with efficient radionuclide uptake. Nanomedicine: Nanotechnology, Biology and Medicine. 41: 102529.PMID: 35104671Poojari R, Mohanty B, Kadwad V, Suryawanshi D, Chaudhari P, Khade B, Srivastava R, Gupta S, Panda D
A Phagosomally Expressed Gene, rv0428c, of Mycobacterium tuberculosis Demonstrates Acetyl Transferase Activity and Plays a Protective Role Under Stress Conditions. Protein Journal.41(2):260-273. PMID: 35175508Sharma A, Kumar A, Rashid M, Amnekar RV, Gupta S, Kaur J
- 2021Tumor-specific overexpression of histone gene, H3C14 in gastric cancer is mediated through EGFR-FOXC1 axis.Biochimica ET Biophysica Acta (BBA) - Gene Regulatory Mechanisms.13:194703. PMID: 33727172
Rashid M, Shah SG, Verma T, Chaudhary N, Sukanya, Patel VB, Gera PB, Smoot D, Ashaktorab H, Dalal SN, Gupta S (2021)
Effect of low frequency electrical current on the biophysical and molecular properties of cancer cells. International Journal of Cancer and Clinical Research. 8:145.Sengupta A, Gupta S, Sharda A, Hemant S, Ingle A (2021)
Atypical activation of signaling downstream of inactivated Bcr-Abl mediates chemoresistance in chronic myeloid leukemia. Journal of Cell Communication and Signaling.Narasimhan M, Khamkar V, Tilwani S, Dalal SN, Shetty D, Subramanian PG, Gupta S, Govekar R
DNA methylation mediated downregulation of histone 53 variant H3.3 affects cell proliferation contributing to the development of HCC.Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.Reddy D, Bhattacharya S, Shah S, Rashid M, Gupta S
Hepatocellular Carcinoma: Understanding Molecular Mechanisms for Defining Potential Clinical Modalities. World Journal of Hepatology (in press)Abhiram Natu, Anjali Singh and Sanjay Gupta
In-Silico Analysis of Chromatin Modifiers and Profiling of Histone Deacetylases in Human Oral Cancer. Chonnam Medical Journal.Anand K. Sajnani, Sanket G. Shah, Mudasir Rashid, Abhiram Natu, Poonam B. Gera, and Sanjay Gupta
RPS13, a potential universal reference gene for normalisation of gene expression in multiple human normal and cancer tissue samples. Molecular Biology Reports.Mudasir Rashid, Sanket Girish Shah, Abhiram Natu, Tripti Verma, Sukanya, Poonam B. Gera, Sanjay Gupta
ERK1/2-EGR1-SRSF10 axis mediated alternative splicing promotes head and neck oncogenesis, Frontiers in Cell and Developmental Biology (Epigenomics and Epigenetics), 20 September 2021 | https://doi.org/10.3389/fcell.2021.713661Sandhya Yadav, Deepak Pant, Atul Samaiya, Sanjay Gupta, Sanjeev Shukla
Lipocalin 2 expression promotes tumor progression and therapy resistance by inhibiting ferroptosis in colorectal cancer. Int J Cancer;149(7):1495-1511. doi: 10.1002/ijc.33711.Chaudhary, N., Choudhary, B. S., Shah, S. G., Khapare, N., Dwivedi, N., Gaikwad, A., Joshi, N., Raichanna, J., Basu, S., Gurjar, M., Smitha, P. K., Saklani, A., Gera, P., Ramadwar, M., Patil, P., Thorat, R., Gota, V., Dhar, S. K., Gupta, S., Das, M., and Dalal, S. N.
- 2020Chromatin, histones, and histone modifications in health and diseases (2020). In ‘Genome Plasticity in Health and Disease’ (1st Edition) Editors: Diego Forero & George Patrinos, ISBN: 9780128178195, Academic Press.
Sanket G. Shah, Mudasir Rashid, Tripti Verma, Sanjay Gupta
Sfrp1 in skin tumor initiation and cancer stem cell regulation with potential implications in epithelial cancers (2020). Stem Cell Reports (in press)Raghava R Sunkara, Rahul M Sarate, Priyanka Setia, Sanket Shah, Sanjay Gupta, Poonam Gera, Pankaj Chaturvedi, Sanjeev Waghmare
Histone deacetylase inhibitor pre-treatment enhances the efficacy of DNA-interacting chemotherapeutic drugs in gastric cancer (2020). World J Gastroenterol 2020 February 14; 26(6): 598-613Ramchandra V Amnekar, Shafqat A Khan, Mudasir Rashid, Bharat Khade, Rahul Thorat, Poonam Gera, Shailesh V Shrikhande, Duane T Smoot, Hassan Ashktorab, Sanjay Gupta
Histone H2A isoforms: Potential implications in epigenome plasticity and diseases in eukaryotes (2020). J of Biosciences 45:4Sanket G. Shah, Tripti Verma, Mudasir Rashid, Nikhil Gadewal, Sanjay Gupta
Elevated HDAC activity and altered histone phospho-acetylation confer acquired radio-resistant phenotype to breast cancer cells (2020) Clinical Epigenetics. 12:4Asmita Sharda, Mudasir Rashid, Sanket Shah, Ajit Kumar Sharma, Saurav Raj Singh, Poonam Gera, Murali Krishna Chilakapati, Sanjay Gupta
HISTome2: a database of histone proteins, modifiers for multiple organisms and epidrugs. Epigenetics & Chromatin; 13: 31 (2020)Sanket G. Shah, Tushar Mandloi, Pooja Kunte, Abhiram Natu, Mudasir Rashid, Divya Reddy, Nikhil Gadewal & Sanjay Gupta
- 2019Histone Post-Translational Modifications: Potential Role in Diagnosis, Prognosis and Therapeutics of Cancer. In Book ‘Prognostic epigenetics’. (2019) Volume 15: 351-373 in Prognostic Epigenetics Series Translational Epigenetics, 2019, Publisher Elsevier
Asmita Sharda, Ramchandra V. Amnekar, Abhiram Natu, Sukanya and Sanjay Gupta
Establishing a correlation between RIN and A260/280 along with the multivariate evaluation of factors affecting the quality of RNA in cryopreserved cancer bio-specimen. Cell Tissue Bank (2019). https://doi.org/10.1007/s10561-019-09782-7Sanket G. Shah, Mudasir Rashid, Tripti Verma, Madan Ludbe, Bharat Khade, Poonam B. Gera, Sanjay Gupta
Cationic cholesterol derivative efficiently delivers the genes: In-silico and In-vitro studies. Drug Delivery and Translational Research, 2019 Feb; 9(1):106-122Jasmin Monpara, Divya Velga, Tripti Verma, Sanjay Gupta, and Pradeep Vavia
- 2018Plakophilin3 increases desmosome assembly, size and stability by increasing expression of desmocollin. Biochem Biophys Res Commun. 2018 Jan 1;495(1):768-774
Mansa Gurjar, Kumarkrishna Raychaudhuri, Snehal Mahadik, Divya Reddy, Apurva Atak, Trupti Shetty, Kruthi Rao, Mansi S Karkhanis, Prajakta Gosavi, Lalit Sehgal, Sanjay Gupta, Sorab Nariman Dalal
Biochemical and Biophysical characterization of higher oligomeric structure of Rat Nucleosome Assembly Protein 1. The Protein Journal, 2018Divya Reddy, Saikat Bhattacharya, Vinod Jani, Uddhavesh Sonawane, Rajendra Joshi and Sanjay Gupta
Plakophilin3 loss leads to an increase in lipocalin2 expression, which is required for tumour formation. Exp Cell Res. 2018Basu S, Chaudhary N, Shah S, Braggs C, Sawant A, Vaz S, Thorat R, Gupta S, Dalal SN
Repositioning of difluorinated propanediones as inhibitors of histone methyltransferases and their biological evaluation in human leukemic cell lines. Anticancer Agents Med Chem. 2018Pal T, Sharda A, Khade B, Ramaa CS, Gupta S
HDAC inhibitors in solid tumors: An incomplete story. J Clin Epigenetics. 4(2):8, 2018 (Editorial)Amnekar RV, Gupta S
Hyperbaric Oxygen Therapy (HBO), DNA Damage and Tumor Progression - A Survival Study on a Mice Tumor Model. Journal of Cancer Biology & Research. J Cancer Biol Res 6(1): 1113 (2018)Amit Sengupta, Sanjay Gupta, Arvind Ingle, and Jayant Goda
- 2017Histone isoform H2A1H promotes attainment of distinct physiological states by altering chromatin dynamics. Epigenetics and Chromatin. 10:48, 2017
Saikat Bhattacharya; Divya Reddy; Vinod Jani; Nikhil Gadewal; Sanket Shah; Raja Reddy; Uddhavesh Sonawane; Kakoli Bose; Rajendra Joshi; Sanjay Gupta
Chromatin landscape: Re-shaping radiation biology and oncology. Journal of Radiation and Cancer Research, 3: 8, 2017 (Editorial)Asmita Sharda and Sanjay Gupta
A novel method for isolation of histones from serum and its implications in therapeutics and prognosis of solid tumors. Clinical Epigenetics. 9:30, 2017Divya Reddy, Bharat Khade, Riddhi Pandya and Sanjay Gupta
Genomic characterization and dynamic methylation of promoter facilitates transcriptional regulation of H2A variants, H2A.1 and H2A.2 in various pathophysiological states of hepatocyte. The International Journal of Biochemistry & Cell Biology. 85:15-24. 2017* equal contributionMonica Tyagi*, Divya Reddy* and Sanjay Gupta
- 2016p38-MAPK/MSK1-mediated overexpression of histone H3 serine 10 phosphorylation defines distance-dependent prognostic value of negative resection margin in gastric cancer. Clinical Epigenetics, 8:88, 2016
Shafqat Ali Khan, Ramchandra Amnekar, Bharat Khade, Savio George Barreto, Mukta Ramadwar, Shailesh V. Shrikhande and Sanjay Gupta
Preliminary evaluation of indigenous 90Y-labeled Microspheres for therapy of hepatocellular carcinoma. Indian Journal of Medical Research, 143:74-81, 2016Suresh Subramanian, Usha Pandey, Pradip Chaudhari, Monica Tyagi, Sanjay Gupta, Geetanjali Singh, Ashutosh Dash, Grace Samuel, Meera Venkatesh
Incorporation of a tag helps to overcome expression variability in a recombinant host. Biotechnology Reports 11; 62–69, 2016Saikat Bhattacharya, Divya Reddy, Raja Reddy, Asmita Sharda, Kakoli Bose, Sanjay Gupta
sPLA2 -IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induce Differentiation Mediated through Enhanced JNK/c-Jun Activation. Stem Cells, 34(9):2407-17, 2016Rahul M. Sarate, Gopal L. Chovatiya, Vagisha Ravi, Bharat Khade, Sanjay Gupta, Sanjeev K. Waghmare
Histone H2A Mono-ubiquitination and Cellular Transformation are Inversely Related in N-nitrosodiethylamine-induced Hepatocellular Carcinoma. Experimental Biology and Medicine, 241: 1739–1744, 2016Saikat Bhattacharya, Divya Reddy, Arvind Ingle, Bharat Khade, Sanjay Gupta
A Simple Method to Produce Sub-Nucleosome omplexes of High Purity In Vitro, Advances in Biosciences and Biotechnology, 7, 131-141Saikat Bhattacharya and Sanjay Gupta
- 2015Global Histone Posttranslational Modifications and Cancer: Biomarkers for Diagnosis, Treatment and Prognosis? World Journal of Biological Chemistry, 6(4): 333–345, 2015
Shafqat A. Khan, Divya R Velga, Sanjay Gupta
MKP1 phosphatase mediates G1-specific dephosphorylation of H3Serine10P in response to DNA damage Mutation Research, 778:71-9, 2015Ajit K. Sharma, Shafqat A. Khan, Asmita Sharda, Divya R Velga, Sanjay Gupta
Dynamic alteration in H3 serine 10 phosphorylation is G1-phasespecific during ionization radiation induced DNA damage response inhuman cells. Mutation Research, 773: 83–91Ajit K. Sharma, Saikat Bhattacharya, Shafqat A. Khan, Bharat Khade, Sanjay Gupta
Techniques to Access Histone Modifications and Variants in Cancer. ‘Cancer Epigenetics: Risk Assessment, Diagnosis, Treatment, and Prognosis’, Methods in Molecular Biology Series (Humana Press/Springer) 2015Monica Tyagi, Shafqat A Khan, Saikat Bhattacharya, Divya Reddy, Ajit K Sharma, Bharat Khade, Sanjay Gupta
- 2014Self-assembled nanocomplexes of anionic pullulan and polyallylamine for DNA and pH sensitive intracellular drug delivery. Journal of Nanoparticle Research. 16:2781, 2014
Lalit Vora, Monica Tyagi, Ketan Patel, Sanjay Gupta and Pradeep Vavia
Cell-type specificity of β-actin expression and its clinicopathological correlation in gastric adenocarcinoma. World Journal of Gastroenterology, 20(34):12202-11. 2014Shafqat A Khan, Monica Tyagi, Ajit K Sharma, Savio G Barreto, Bhawna Sirohi, Mukta Ramadwar, Shailesh V Shrikhande, Sanjay Gupta
Histone Chaperones: Functions beyond Nucleosome Deposition. Advances in Bioscience and Biotechnology, 5:6, 2014Divya Reddy, Saikat Bhattacharya, Sanjay Gupta
Expression of histone variant, H2A.1 is associated with the undifferentiated state of hepatocyte, Experimental Biology and Medicine.239 (10):1335-9, 2014Monica Tyagi, Bharat Khade, Shafqat A Khan, Arvind Ingle, Sanjay Gupta
Arginoplexes: an arginine-anchored nanoliposomal carrier for gene delivery. Journal of Nanoparticle Research, 16: 2345, 2014Ketan Patel, Monica Tyagi, Jasmin Monpara, Lalit Vora, Sanjay Gupta, Pradeep Vavia
Histone Post-translational Modifications as biomarks in cancer: Dream or Reality? Proteomics Society , India (PSI) News Letter Vol. 2 (No.1) April 2014Monica Tyagi, Shafqat A Khan and Sanjay Gupta
- 2013Molecular Modeling of Differentially Phosphorylated Serine 10 and Acetylated lysine 9/14 of Histone H3 regulates their Interactions with 14-3-3ζ, MSK1, and MKP1. Bioinformatics and Biology Insights, 7: 272-288,
Sharma AK, Mansukh A, Varma A, Gadewal, Gupta S.
- 2012HIstome: a relational knowledgebase of human histone proteins and histone modifying enzymes. Nucleic Acids Research, 40D: 337-342, 2012.†Corresponding authors
Khare SP, Habib F, Sharma R, Gadewal N, Gupta S†, Galande S†
- 2011Overexpression of histone variant H2A.1 and cellular transformation are related in N-Nitrosodiethylamine induced sequential hepatocarcinogenesis. Experimental Biology and Medicine, 236 (1): 30-5
Khare S, Sharma A, Deodhar K K, Gupta S
Hepatoprotective effects of aqueous leaf extract and crude isolates of Murraya koenigii against in vitro ethanol-induced hepatotoxicity model. Experimental and Toxicologic Pathology, 63 (6):587-91Sadhana S, Bagula Y, Gupta S, Kaura H, Redkara R.
- 2010
- 2009Sida rhombifolia ssp. retusa Seed Extract Inhibits DEN Induced Murine Hepatic Preneoplasia and Carbon Tetrachloride Hepatotoxicity. Asian Pacific Journal of Cancer Prevention, 10, 1107-1112
Poojari R, Gupta S, Maru G, Khade B, Bhagwat S
Mass spectrometry compatible silver staining of histones resolved on Acetic acid-Urea-Triton PAGE. Proteomics. 9 (9):2589-92Khare S, Khade B and Gupta S
- 2008Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action. Carcinogenesis. 29(5):1022-1032
Garg R, Gupta S and Maru G B
- 2006DNA methylation induced changes in chromatin conformation of the promoter of vitellogenin II gene of Japanese quail. During aging. Gene, Section: Functional Genomics, 377: 159-68
Gupta S, Pathak R U and Kanungo MS
- 2004Hyperphosphorylation of extracellular regulated kinase 2 (ERK2) and inhibition of JNK 2 phosphorylation are associated with increased S-phase during of transformation of Syrian hamster embryo cells by Malachite green. Cell Biology International, 28, 875-8
Bose B, Gour RR, Motiwale L, Gupta S and Rao KVK.
- 2003Tumor promotion by metanil yellow and malachite green during rat hepatocarcinogenesis is associated with dysregulated expression of cell cycle regulatory proteins. Teratogenesis, Carcinogenesis & Mutagenesis, 1:301-312
Gupta S, Sundarrajan M and Rao KVK